▪ Esomeprazole offers Faster onset of action, compared to all PPI’s. ▪ ESOZ keeps intragastric pH at >4.0 for 5 more hours than pantoprazole. ▪ ESOZ provides faster & predictable onset of action. ▪ Once daily dose. ▪ Increases glycemic control in Insulin dependent Diabetes Mellitus, manages Gastroparesis.